Issue 65, 2019
From the journal:

Chemical Communications

Ultrasensitive photoelectrochemical biosensor for MiRNA-21 assay based on target-catalyzed hairpin assembly coupled with distance-controllable multiple signal amplification†

Ming-Hui Zhu,a   Xiao-Mei Mu,a   Han-Mei Deng,a   Xia Zhong,a   Ruo Yuan ORCID logo *a  and  Ya-Li Yuan ORCID logo *a  

* Corresponding authors

a Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, P. R. China
E-mail: yuanruo@swu.edu.cn, y198688@swu.edu.cn
Fax: +86-23-68253172
Tel: +86-23-68252277

Abstract

Here, with the target-catalyzed hairpin assembly generated dsDNA (HP1-HP2) to synchronously control the departure of quencher ferrocene and approach of sensitizer methylene blue, a distance-controllable multiple signal amplification based photoelectrochemical biosensor was proposed for MiRNA-21 assay.

Graphical abstract: Ultrasensitive photoelectrochemical biosensor for MiRNA-21 assay based on target-catalyzed hairpin assembly coupled with distance-controllable multiple signal amplification

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Article information

DOI
https://doi.org/10.1039/C9CC04987H
Article type
Communication
Submitted
29 Jun 2019
Accepted
16 Jul 2019
First published
16 Jul 2019

Chem. Commun., 2019,55, 9622-9625

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Ultrasensitive photoelectrochemical biosensor for MiRNA-21 assay based on target-catalyzed hairpin assembly coupled with distance-controllable multiple signal amplification

M. Zhu, X. Mu, H. Deng, X. Zhong, R. Yuan and Y. Yuan, Chem. Commun., 2019, 55, 9622 DOI: 10.1039/C9CC04987H

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