Issue 83, 2019

The remarkable UV light invulnerability of thymine GNA dinucleotides

Abstract

We herein demonstrate the UV resistance of glycol nucleic acid (GNA) dinucleotides. This resistance sustains the hypothesis of GNA as a nucleic acid prebiotic ancestor on early Earth, a time of intense solar UV light. Such photorobustness, due to the absence of intrastrand base stacking, could offer an opportunity for nanodevice development requiring challenging UV conditions.

Graphical abstract: The remarkable UV light invulnerability of thymine GNA dinucleotides

Supplementary files

Article information

Article type
Communication
Submitted
06 Jun 2019
Accepted
25 Sep 2019
First published
25 Sep 2019

Chem. Commun., 2019,55, 12571-12574

The remarkable UV light invulnerability of thymine GNA dinucleotides

S. Coantic-Castex, A. Martinez, D. Harakat, D. Guillaume and P. Clivio, Chem. Commun., 2019, 55, 12571 DOI: 10.1039/C9CC04355A

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