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Issue 57, 2019
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Organotin(iv) differential fluorescent probe for controlled subcellular localization and nuclear microviscosity monitoring

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Abstract

A dual-emissive fluorescent probe enabling dynamic changes in nuclear local microviscosity monitoring was developed. The new sensing scenario involves probe subcellular localization redistribution, allowing a quantitative analysis of the local microviscosity related to nuclear damage in the presence of agents perturbing the nuclear morphology. With the aid of an organotin(IV) in situ formed complex we propose a different scenario of bioanalytical applications through confocal microscopy.

Graphical abstract: Organotin(iv) differential fluorescent probe for controlled subcellular localization and nuclear microviscosity monitoring

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Article information


Submitted
30 May 2019
Accepted
20 Jun 2019
First published
20 Jun 2019

Chem. Commun., 2019,55, 8246-8249
Article type
Communication

Organotin(IV) differential fluorescent probe for controlled subcellular localization and nuclear microviscosity monitoring

J. Bernal-Escalante, A. López-Vázquez, D. Araiza-Olivera and A. Jiménez-Sánchez, Chem. Commun., 2019, 55, 8246
DOI: 10.1039/C9CC04179F

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