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Issue 65, 2019
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A dual-mode nanoprobe for evaluation of the autophagy level affected by photothermal therapy

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Abstract

A novel dual-mode nanoprobe (Apt@MNPS) was created for the detection of autophagy-related miRNAs to monitor the autophagic level and study the effect of PTT on autophagy. Interestingly, using our developed probe, PTT was found to be able to activate the autophagy by down regulation of miR-18a* and miR-4802, which in turn restricted the PTT efficiency for cancer.

Graphical abstract: A dual-mode nanoprobe for evaluation of the autophagy level affected by photothermal therapy

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Publication details

The article was received on 30 Apr 2019, accepted on 15 Jul 2019 and first published on 16 Jul 2019


Article type: Communication
DOI: 10.1039/C9CC03319J
Chem. Commun., 2019,55, 9673-9676

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    A dual-mode nanoprobe for evaluation of the autophagy level affected by photothermal therapy

    J. Liu, Y. Qu, T. Zheng and Y. Tian, Chem. Commun., 2019, 55, 9673
    DOI: 10.1039/C9CC03319J

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