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Issue 49, 2019
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Development of a red absorbing Se-rhodamine photosensitizer and its application for bio-orthogonally activatable photodynamic therapy

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Abstract

A π-extended red absorbing Se-rhodamine (Se-NR) was synthesised and characterized. By masking the amine of Se-NR as an azide, we successfully constructed a bio-orthogonally activatable photosensitizer (Se-NR-Az). Se-NR-Az was not photocytotoxic, but when activated by the Staudinger reaction, photocytotoxicity was restored.

Graphical abstract: Development of a red absorbing Se-rhodamine photosensitizer and its application for bio-orthogonally activatable photodynamic therapy

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Publication details

The article was received on 18 Apr 2019, accepted on 23 May 2019 and first published on 23 May 2019


Article type: Communication
DOI: 10.1039/C9CC03018B
Chem. Commun., 2019,55, 7037-7040

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    Development of a red absorbing Se-rhodamine photosensitizer and its application for bio-orthogonally activatable photodynamic therapy

    W. Lv, S. Chi, W. Feng, T. Liang, D. Song and Z. Liu, Chem. Commun., 2019, 55, 7037
    DOI: 10.1039/C9CC03018B

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