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Issue 35, 2019
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Programming a split G-quadruplex in a DNA nanocage and its microRNA imaging in live cells

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Abstract

A novel approach to program target-responsive devices by incorporating the split G4 motifs in a DNA nanocage has been developed. The rigid prism outcompetes the flexible one in reaction kinetics and signal/background ratios, which can be easily internalized by cells and successfully applied in microRNA imaging in live cells.

Graphical abstract: Programming a split G-quadruplex in a DNA nanocage and its microRNA imaging in live cells

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Article information


Submitted
14 Mar 2019
Accepted
01 Apr 2019
First published
01 Apr 2019

Chem. Commun., 2019,55, 5131-5134
Article type
Communication

Programming a split G-quadruplex in a DNA nanocage and its microRNA imaging in live cells

Y. Yu, Y. Zhou, M. Zhu, M. Liu, H. Zhu, Y. Chen, G. Su, W. Chen and H. Peng, Chem. Commun., 2019, 55, 5131
DOI: 10.1039/C9CC02096A

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