Issue 42, 2019

Multifunctional isoquinoline-oxazoline ligands of chemical and biological importance

Abstract

Multifunctional isoquinoline-oxazolines (MIQOXs) were conceived and synthesized from commercially available chiral amino acids. The multifunctional role of MIQOXs was demonstrated by Pd-catalyzed highly enantioselective addition of arylboronic acids to nitrostyrenes, and by the discovery of novel antifungal candidates.

Graphical abstract: Multifunctional isoquinoline-oxazoline ligands of chemical and biological importance

Supplementary files

Article information

Article type
Communication
Submitted
05 Mar 2019
Accepted
25 Apr 2019
First published
25 Apr 2019

Chem. Commun., 2019,55, 5902-5905

Multifunctional isoquinoline-oxazoline ligands of chemical and biological importance

W. Li, G. Wang, J. Lai and S. Li, Chem. Commun., 2019, 55, 5902 DOI: 10.1039/C9CC01790A

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