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Issue 15, 2019
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Homogenous deposition of matrix–analyte cocrystals on gold-nanobowl arrays for improving MALDI-MS signal reproducibility

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Abstract

The non-uniform deposition of matrix–analyte cocrystals and poor ionization are major obstacles in quantitative analysis through MALDI-MS. An Au-nanobowl array was prepared and applied to overcome these limitations, which enabled the quantitative detection of oligonucleotides and polypeptides.

Graphical abstract: Homogenous deposition of matrix–analyte cocrystals on gold-nanobowl arrays for improving MALDI-MS signal reproducibility

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Article information


Submitted
18 Dec 2018
Accepted
15 Jan 2019
First published
22 Jan 2019

Chem. Commun., 2019,55, 2166-2169
Article type
Communication

Homogenous deposition of matrix–analyte cocrystals on gold-nanobowl arrays for improving MALDI-MS signal reproducibility

W. Li, M. Khan, H. Li, L. Lin, S. Mao and J. Lin, Chem. Commun., 2019, 55, 2166
DOI: 10.1039/C8CC09945F

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