Issue 12, 2019

Real-time visualization of autophagy by monitoring the fluctuation of lysosomal pH with a ratiometric two-photon fluorescent probe

Abstract

A benzimidazole-decorated two-photon fluorescent probe (Lyso-MPCB) based on the p-methoxyphenylacetylene-substituted carbazole was developed for detecting lysosomal pH with a double-channel signal, which can be used to visualize autophagy by real-time imaging the fluctuation of the pH in the lysosomes.

Graphical abstract: Real-time visualization of autophagy by monitoring the fluctuation of lysosomal pH with a ratiometric two-photon fluorescent probe

Supplementary files

Article information

Article type
Communication
Submitted
30 Nov 2018
Accepted
10 Jan 2019
First published
11 Jan 2019

Chem. Commun., 2019,55, 1782-1785

Real-time visualization of autophagy by monitoring the fluctuation of lysosomal pH with a ratiometric two-photon fluorescent probe

P. Ning, L. Hou, Y. Feng, G. Xu, Y. Bai, H. Yu and X. Meng, Chem. Commun., 2019, 55, 1782 DOI: 10.1039/C8CC09517E

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