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Issue 4, 2019
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A rhodamine based fluorescent probe validates substrate and cellular hypoxia specific NADH expression

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Abstract

Herein, we report a rhodamine-based redox probe (MQR) to visualize cytosolic NADH in the cellular milieu. Its high sensitivity and selectivity allowed it to track the alteration of the NADH level under metabolic perturbation, suggesting its potential as a useful tool to study the association between the NADH level and metabolic abnormalities with clinical significance.

Graphical abstract: A rhodamine based fluorescent probe validates substrate and cellular hypoxia specific NADH expression

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Publication details

The article was received on 12 Nov 2018, accepted on 03 Dec 2018 and first published on 04 Dec 2018


Article type: Communication
DOI: 10.1039/C8CC08991D
Chem. Commun., 2019,55, 537-540

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    A rhodamine based fluorescent probe validates substrate and cellular hypoxia specific NADH expression

    A. Podder, S. Koo, J. Lee, S. Mun, S. Khatun, H. Kang, S. Bhuniya and J. S. Kim, Chem. Commun., 2019, 55, 537
    DOI: 10.1039/C8CC08991D

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