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Issue 4, 2019
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Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies: in vivo imaging of diesel exhaust particulates in mice

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Abstract

As a robust radioanalytical method for tracking carbonaceous particulates in vivo, polycyclic aromatic hydrocarbons from diesel exhaust were labeled with a radioactive-iodine-tagged pyrene analogue. Single-photon emission computed tomography and biodistribution studies showed high uptake and slow clearance of this matter in the respiratory system, which may underlie its severe toxicity.

Graphical abstract: Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies: in vivo imaging of diesel exhaust particulates in mice

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Publication details

The article was received on 17 Oct 2018, accepted on 13 Nov 2018 and first published on 26 Nov 2018


Article type: Communication
DOI: 10.1039/C8CC08304E
Citation: Chem. Commun., 2019,55, 447-450
  • Open access: Creative Commons BY license
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    Efficient and stable radiolabeling of polycyclic aromatic hydrocarbon assemblies: in vivo imaging of diesel exhaust particulates in mice

    C. H. Lee, H. E. Shim, L. Song, H. G. Moon, K. Lee, J. E. Yang, H. Y. Song, Y. J. Choi, D. S. Choi and J. Jeon, Chem. Commun., 2019, 55, 447
    DOI: 10.1039/C8CC08304E

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