Issue 93, 2018

Enhancing intracellular microRNA imaging: a new strategy combining double-channel exciting single colour fluorescence with the target cycling amplification reaction

Abstract

A microRNA (miRNA) fluorescence (FL) nanoprobe based on PDA-UCNPs@FAM-LLD@AuNPs was developed, which exhibited an enhanced signal for imaging intracellular miRNA by combining double-channel exciting single colour FL (DCESCF) with the target cycling amplification reaction. Through this strategy, normal cells and cancer cells could be successfully discriminated.

Graphical abstract: Enhancing intracellular microRNA imaging: a new strategy combining double-channel exciting single colour fluorescence with the target cycling amplification reaction

Supplementary files

Article information

Article type
Communication
Submitted
01 Sep 2018
Accepted
24 Oct 2018
First published
25 Oct 2018

Chem. Commun., 2018,54, 13131-13134

Enhancing intracellular microRNA imaging: a new strategy combining double-channel exciting single colour fluorescence with the target cycling amplification reaction

K. Zhang, S. Song, L. Yang, Q. Min, X. Wu and J. Zhu, Chem. Commun., 2018, 54, 13131 DOI: 10.1039/C8CC07112H

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