Issue 83, 2018

Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations

Abstract

To address the challenges associated with glycan analyses, we have implemented a structures for lossless ion manipulations (SLIM) serpentine ultra-long path with extended routing (SUPER) ion mobility-mass spectrometry (i.e. SLIM SUPER IM-MS) platform to achieve much higher resolution of isomeric glycoforms. We have demonstrated the potential of this platform as a future component of the glycomics toolbox.

Graphical abstract: Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations

Supplementary files

Article information

Article type
Communication
Submitted
27 Aug 2018
Accepted
21 Sep 2018
First published
25 Sep 2018

Chem. Commun., 2018,54, 11701-11704

Unraveling the isomeric heterogeneity of glycans: ion mobility separations in structures for lossless ion manipulations

G. Nagy, I. K. Attah, S. V. B. Garimella, K. Tang, Y. M. Ibrahim, E. S. Baker and R. D. Smith, Chem. Commun., 2018, 54, 11701 DOI: 10.1039/C8CC06966B

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