Jump to main content
Jump to site search
Access to RSC content Close the message box

Continue to access RSC content when you are not at your institution. Follow our step-by-step guide.


Issue 79, 2018
Previous Article Next Article

Lewis acid-catalyzed Friedel–Crafts reactions toward highly versatile, α-quaternary oxime ethers

Author affiliations

Abstract

The synthesis of all-carbon-substituted, quaternary stereocenters through Lewis acid-catalyzed Friedel–Crafts alkylation of cyclic and acyclic 2-hydroxy oxime ethers proceeds under mild reaction conditions and with high yields. Moreover, the oxime ether moiety can be easily manipulated into various functional groups through subsequent modifications.

Graphical abstract: Lewis acid-catalyzed Friedel–Crafts reactions toward highly versatile, α-quaternary oxime ethers

Back to tab navigation

Supplementary files

Article information


Submitted
22 Aug 2018
Accepted
10 Sep 2018
First published
11 Sep 2018

Chem. Commun., 2018,54, 11124-11127
Article type
Communication

Lewis acid-catalyzed Friedel–Crafts reactions toward highly versatile, α-quaternary oxime ethers

M. Schlegel and C. Schneider, Chem. Commun., 2018, 54, 11124
DOI: 10.1039/C8CC06823B

Social activity

Search articles by author

Spotlight

Advertisements