Jump to main content
Jump to site search

Issue 67, 2018
Previous Article Next Article

Matrix metalloproteinase targeted peptide vesicles for delivering anticancer drugs

Author affiliations

Abstract

A matrix metalloproteinase (MMP) targeted tetrapeptide vesicle has been designed and developed, which strongly binds at a MMP9 enzymatic site. Interestingly, it has a propensity to encapsulate and deliver the doxorubicin drug specifically to the cancer cell, induces superior apoptotic death, and inhibits the metastatic cancer cell migration and growth of multicellular 3D spheroids.

Graphical abstract: Matrix metalloproteinase targeted peptide vesicles for delivering anticancer drugs

Back to tab navigation

Supplementary files

Publication details

The article was received on 13 Jul 2018, accepted on 24 Jul 2018 and first published on 24 Jul 2018


Article type: Communication
DOI: 10.1039/C8CC05687K
Chem. Commun., 2018,54, 9309-9312

  •   Request permissions

    Matrix metalloproteinase targeted peptide vesicles for delivering anticancer drugs

    D. Bhunia, K. Pradhan, G. Das, S. Ghosh, P. Mondal and S. Ghosh, Chem. Commun., 2018, 54, 9309
    DOI: 10.1039/C8CC05687K

Search articles by author

Spotlight

Advertisements