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Issue 83, 2018
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Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(iv)

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Abstract

Up until now, molecular chelating agents, such as diethylenetriamine pentaacetic acid (DTPA), have been the standard method for actinide human decorporation. Mainly active in blood serum, their distribution within the body is thus limited. To treat a wider range of organs affected by plutonium contamination, a potential new class of macromolecular decorporation agents is being studied. Polyethyleneimine methylenecarboxylate (PEI-MC) is one such example. It is being considered here because of its capacity for targeting the liver and bones.

Graphical abstract: Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(iv)

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Article information


Submitted
29 Jun 2018
Accepted
24 Sep 2018
First published
25 Sep 2018

Chem. Commun., 2018,54, 11705-11708
Article type
Communication

Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(IV)

F. Lahrouch, B. Siberchicot, L. Leost, J. Aupiais, A. Rossberg, C. Hennig, C. Den Auwer and C. Di Giorgio, Chem. Commun., 2018, 54, 11705
DOI: 10.1039/C8CC05206A

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