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Issue 81, 2018
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A novel nucleic acid aptamer tag: a rapid fluorescence strategy using a self-constructing G-quadruplex from AGG trinucleotide repeats

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Abstract

Herein, we have developed a novel fluorescence labeling strategy for nucleic acid aptamers based on self-assembling between AGG tri-nucleotide repeats and a pyrene-modified oligonucleotide. This strategy could be an effective tool for developing targeting–imaging systems and biosensor systems to detect target molecules.

Graphical abstract: A novel nucleic acid aptamer tag: a rapid fluorescence strategy using a self-constructing G-quadruplex from AGG trinucleotide repeats

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Publication details

The article was received on 30 Jun 2018, accepted on 14 Sep 2018 and first published on 17 Sep 2018


Article type: Communication
DOI: 10.1039/C8CC05197F
Citation: Chem. Commun., 2018,54, 11487-11490

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    A novel nucleic acid aptamer tag: a rapid fluorescence strategy using a self-constructing G-quadruplex from AGG trinucleotide repeats

    B. Fu, Y. Park, K. T. Kim, K. Chen, G. Zou, Q. Wei, S. Peng, Y. Chen, B. H. Kim and X. Zhou, Chem. Commun., 2018, 54, 11487
    DOI: 10.1039/C8CC05197F

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