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Issue 55, 2018
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Enhancing the efficacy of photodynamic therapy (PDT) via water-soluble pillar[5]arene-based supramolecular complexes

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Abstract

A supramolecular nanovesicle was constructed by complexation between pyrophaeophorbide A (PPhA) and water-soluble pillar[5]arene, and then a biotin–pyridinium targeting agent was introduced to its surface. This nanovesicle exhibited reduced aggregation of PPhA photosensitizers and high targeting ability towards cancer cells, thereby leading to excellent therapeutic efficacy under red light.

Graphical abstract: Enhancing the efficacy of photodynamic therapy (PDT) via water-soluble pillar[5]arene-based supramolecular complexes

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Publication details

The article was received on 29 May 2018, accepted on 14 Jun 2018 and first published on 16 Jun 2018


Article type: Communication
DOI: 10.1039/C8CC04275F
Citation: Chem. Commun., 2018,54, 7629-7632
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    Enhancing the efficacy of photodynamic therapy (PDT) via water-soluble pillar[5]arene-based supramolecular complexes

    J. Wu, J. Tian, L. Rui and W. Zhang, Chem. Commun., 2018, 54, 7629
    DOI: 10.1039/C8CC04275F

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