Jump to main content
Jump to site search

Issue 73, 2018
Previous Article Next Article

An anion receptor that facilitates transmembrane proton–anion symport by deprotonating its sulfonamide N–H proton

Author affiliations

Abstract

Indole-based amide-sulfonamide derivatives were synthesized. The X-ray crystal structure and chloride binding studies in solution showed a 1 : 1 stoichiometry. The ion transport efficiency directly correlated to the pKa of the sulfonamide N–H protons. The mechanistic study indicated proton–anion symport across the lipid bilayer membrane.

Graphical abstract: An anion receptor that facilitates transmembrane proton–anion symport by deprotonating its sulfonamide N–H proton

Back to tab navigation

Supplementary files

Article information


Submitted
21 May 2018
Accepted
09 Aug 2018
First published
09 Aug 2018

Chem. Commun., 2018,54, 10351-10354
Article type
Communication

An anion receptor that facilitates transmembrane proton–anion symport by deprotonating its sulfonamide N–H proton

S. V. Shinde and P. Talukdar, Chem. Commun., 2018, 54, 10351
DOI: 10.1039/C8CC04044C

Social activity

Search articles by author

Spotlight

Advertisements