Issue 57, 2018

Visible-light induced three-component alkynyl-difluoroalkylation of unactivated alkenes

Abstract

A visible-light induced three-component reaction of difluoroalkyl halides, unactivated alkenes, and alkynyl sulfones is described, providing a direct and general approach to the construction of synthetically valuable β-difluoroalkylated alkynes under room temperature conditions. This represents the first intermolecular alkynyl-difluoroalkylation of unactivated alkenes.

Graphical abstract: Visible-light induced three-component alkynyl-difluoroalkylation of unactivated alkenes

Supplementary files

Article information

Article type
Communication
Submitted
18 Apr 2018
Accepted
21 Jun 2018
First published
22 Jun 2018

Chem. Commun., 2018,54, 7924-7927

Visible-light induced three-component alkynyl-difluoroalkylation of unactivated alkenes

W. Jin, M. Wu, Z. Xiong and G. Zhu, Chem. Commun., 2018, 54, 7924 DOI: 10.1039/C8CC03105C

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