Issue 30, 2018
From the journal:

Chemical Communications

Effective formation of stable and versatile double-stranded β-sheets templated by a hydrogen-bonded duplex†

You-Di Shi,a   Quan Tang,a   Ya-Fei Jiang, ORCID logo a   Qiang Pei,a   Hong-Wei Tan, ORCID logo a   Zhong-Lin Lu ORCID logo *a  and  Bing Gong ORCID logo *ab  

* Corresponding authors

a Key Laboratory of Radiopharmaceuticals, Ministry of Education, College of Chemistry, Beijing Normal University, Xinjiekouwai Street 19, Beijing 100875, China
E-mail: luzl@bnu.edu.cn

b Department of Chemistry, The State University of New York at Buffalo, Buffalo, New York 14260, USA
E-mail: bgong@buffalo.ed

Abstract

We report herein an effective approach that is generally applicable for constructing double-stranded β-sheets composed of tetra- and penta-peptides based on a hydrogen-bonded duplex template, regardless of their amino acid sequences and α-helical or β-sheet propensities.

Graphical abstract: Effective formation of stable and versatile double-stranded β-sheets templated by a hydrogen-bonded duplex

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Article information

DOI
https://doi.org/10.1039/C8CC01564C
Article type
Communication
Submitted
26 Feb 2018
Accepted
19 Mar 2018
First published
20 Mar 2018

Chem. Commun., 2018,54, 3719-3722

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Effective formation of stable and versatile double-stranded β-sheets templated by a hydrogen-bonded duplex

Y. Shi, Q. Tang, Y. Jiang, Q. Pei, H. Tan, Z. Lu and B. Gong, Chem. Commun., 2018, 54, 3719 DOI: 10.1039/C8CC01564C

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