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Issue 52, 2018
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In situ semi-quantitative assessment of single-cell viability by resonance Raman spectroscopy

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Abstract

Currently, studies are increasingly focusing on the cytotoxic effects of anticancer drugs. Such investigations urgently warrant the assessment of single-cell viability. Here, we developed a novel method for quantifying single-cell viability with high selectivity by resonance Raman scattering. We report on this powerful tool that will allow researchers to study cellular metabolism at the level of a single cell.

Graphical abstract: In situ semi-quantitative assessment of single-cell viability by resonance Raman spectroscopy

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Supplementary files

Article information


Submitted
15 Feb 2018
Accepted
20 Apr 2018
First published
20 Apr 2018

Chem. Commun., 2018,54, 7135-7138
Article type
Communication

In situ semi-quantitative assessment of single-cell viability by resonance Raman spectroscopy

Z. Mao, Z. Liu, J. Yang, X. Han, B. Zhao and C. Zhao, Chem. Commun., 2018, 54, 7135
DOI: 10.1039/C8CC01336E

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