Issue 13, 2018
From the journal:

Chemical Communications

A self-assembled peroxidase from 5′-GMP and heme†

Deiaa M. Harraza  and  Jeffery T. Davis ORCID logo *a  

* Corresponding authors

a Department of Chemistry & Biochemistry, University of Maryland College Park, MD 20742, USA
E-mail: jdavis@umd.edu

Abstract

Guanosine 5′-monophosphate (5′-GMP) and Fe(III)-heme form a supramolecular catalyst with peroxidase activity. Catalysis, which depends on self-assembly of 5′-GMP into a G-quadruplex that binds hemin, can be modulated by nucleotide concentration, temperature and the identity of the nucleotide's sugar.

Graphical abstract: A self-assembled peroxidase from 5′-GMP and heme

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Article information

DOI
https://doi.org/10.1039/C7CC09900B
Article type
Communication
Submitted
27 Dec 2017
Accepted
16 Jan 2018
First published
17 Jan 2018

Chem. Commun., 2018,54, 1587-1590

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A self-assembled peroxidase from 5′-GMP and heme

D. M. Harraz and J. T. Davis, Chem. Commun., 2018, 54, 1587 DOI: 10.1039/C7CC09900B

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