Jump to main content
Jump to site search
PLANNED MAINTENANCE Close the message box

Scheduled maintenance work on Wednesday 27th March 2019 from 11:00 AM to 1:00 PM (GMT).

During this time our website performance may be temporarily affected. We apologise for any inconvenience this might cause and thank you for your patience.


Issue 12, 2018
Previous Article Next Article

A copper-catalyzed reaction of 3-diazoindolin-2-imines with 2-(phenylamino)ethanols: convenient access to spiro[indoline-3,2′-oxazolidin]-2-imines

Author affiliations

Abstract

3-Diazoindolin-2-imines reacted with chiral 2-(phenylamino)ethanols under copper catalysis to furnish chiral spiro[indoline-3,2′-oxazolidin]-2-imines in good yields with excellent diastereoselectivity. The reaction undergoes a copper-catalyzed cascade process involving the formation of copper carbene, C–N coupling, and C–O coupling.

Graphical abstract: A copper-catalyzed reaction of 3-diazoindolin-2-imines with 2-(phenylamino)ethanols: convenient access to spiro[indoline-3,2′-oxazolidin]-2-imines

Back to tab navigation

Supplementary files

Publication details

The article was received on 11 Dec 2017, accepted on 16 Jan 2018 and first published on 16 Jan 2018


Article type: Communication
DOI: 10.1039/C7CC09488D
Citation: Chem. Commun., 2018,54, 1529-1532

  •   Request permissions

    A copper-catalyzed reaction of 3-diazoindolin-2-imines with 2-(phenylamino)ethanols: convenient access to spiro[indoline-3,2′-oxazolidin]-2-imines

    G. Sheng, S. Ma, S. Bai, J. Mao, P. Lu and Y. Wang, Chem. Commun., 2018, 54, 1529
    DOI: 10.1039/C7CC09488D

Search articles by author

Spotlight

Advertisements