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Issue 13, 2018
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Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors

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Abstract

Both melanoma cells and tissues were allowed to interact with an identical pool of billions of human-safe phage nanofiber clones with each genetically displaying a unique 12-mer peptide at the tips, respectively, resulting in the discovery of bionanofibers displaying a melanoma cell/tissue dual-homing peptide for personalized targeted melanoma therapy.

Graphical abstract: Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors

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Article information


Submitted
25 Nov 2017
Accepted
16 Jan 2018
First published
26 Jan 2018

Chem. Commun., 2018,54, 1631-1634
Article type
Communication

Evolutionary selection of personalized melanoma cell/tissue dual-homing peptides for guiding bionanofibers to malignant tumors

M. Yang, Y. Li, Y. Huai, C. Wang, W. Yi and C. Mao, Chem. Commun., 2018, 54, 1631
DOI: 10.1039/C7CC09077C

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