Issue 16, 2018

Self-assembly of small-molecule fumaramides allows transmembrane chloride channel formation

Abstract

This study reports the formation of self-assembled transmembrane anion channels by small-molecule fumaramides. Such artificial ion channel formation was confirmed by ion transport across liposomes and by planar bilayer conductance measurements. The geometry-optimized model of the channel and Cl ion selectivity within the channel lumen was also illustrated.

Graphical abstract: Self-assembly of small-molecule fumaramides allows transmembrane chloride channel formation

Supplementary files

Article information

Article type
Communication
Submitted
11 Nov 2017
Accepted
05 Jan 2018
First published
05 Jan 2018

Chem. Commun., 2018,54, 2024-2027

Self-assembly of small-molecule fumaramides allows transmembrane chloride channel formation

A. Roy, A. Gautam, J. A. Malla, S. Sarkar, A. Mukherjee and P. Talukdar, Chem. Commun., 2018, 54, 2024 DOI: 10.1039/C7CC08693H

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