Issue 10, 2018
From the journal:

Chemical Communications

Absorbance enhancement of aptamers/GNP enables sensitive protein detection in rat brains†

Jinpeng Mao,a   Muzhen Xu,a   Wenliang Jia  and  Meining Zhang ORCID logo *a  

* Corresponding authors

a Department of Chemistry, Renmin University of China, Beijing, China
E-mail: mnzhang@ruc.edu.cn

Abstract

An absorbance enhanced probe based on gold nanoparticles (GNPs) was proposed for a protein assay in the cerebrospinal fluid of a rat brain. The GNPs, assembled with two aptamers by proximity ligation, have high anti-salt properties, and good selectivity and response toward proteins, such as interferon-gamma, in the brain.

Graphical abstract: Absorbance enhancement of aptamers/GNP enables sensitive protein detection in rat brains

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Article information

DOI
https://doi.org/10.1039/C7CC08636A
Article type
Communication
Submitted
09 Nov 2017
Accepted
05 Jan 2018
First published
05 Jan 2018

Chem. Commun., 2018,54, 1193-1196

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Absorbance enhancement of aptamers/GNP enables sensitive protein detection in rat brains

J. Mao, M. Xu, W. Ji and M. Zhang, Chem. Commun., 2018, 54, 1193 DOI: 10.1039/C7CC08636A

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