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Issue 9, 2018
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In situ fluorescence activation of DNA–silver nanoclusters as a label-free and general strategy for cell nucleus imaging

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Abstract

A facile, general and turn-on nucleus imaging strategy was first developed based on in situ fluorescence activation of C-rich dark silver nanoclusters by G-rich telomeres. After a simple incubation without washing, nanoclusters could selectively stain the nucleus with intense red luminescence, which was confirmed using fixed/living cells and several cell lines.

Graphical abstract: In situ fluorescence activation of DNA–silver nanoclusters as a label-free and general strategy for cell nucleus imaging

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Supplementary files

Article information


Submitted
25 Oct 2017
Accepted
02 Jan 2018
First published
02 Jan 2018

Chem. Commun., 2018,54, 1089-1092
Article type
Communication

In situ fluorescence activation of DNA–silver nanoclusters as a label-free and general strategy for cell nucleus imaging

D. Li, Z. Qiao, Y. Yu, J. Tang, X. He, H. Shi, X. Ye, Y. Lei and K. Wang, Chem. Commun., 2018, 54, 1089
DOI: 10.1039/C7CC08228B

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