Jump to main content
Jump to site search

Issue 3, 2018
Previous Article Next Article

Responsive DNA G-quadruplex micelles

Author affiliations


A novel and versatile design of DNA–lipid conjugates is presented. The assembly of the DNA headgroups into G-quadruplex structures is essential for the formation of micelles and their stability. By hybridization with a complementary oligonucleotide the micelles were destabilized, resulting in cargo release. In combination with a hairpin DNA aptamer as complementary strand, the release is obtained selectively by the presence of ATP.

Graphical abstract: Responsive DNA G-quadruplex micelles

Back to tab navigation

Supplementary files

Article information

16 Oct 2017
06 Dec 2017
First published
06 Dec 2017

Chem. Commun., 2018,54, 260-263
Article type

Responsive DNA G-quadruplex micelles

L. Cozzoli, L. Gjonaj, M. C. A. Stuart, B. Poolman and G. Roelfes, Chem. Commun., 2018, 54, 260
DOI: 10.1039/C7CC07899D

Social activity

Search articles by author