Palladium-catalyzed direct sulfonylation of C–H bonds with the insertion of sulfur dioxide

Abstract

A palladium-catalyzed direct sulfonylation of C–H bonds with the insertion of sulfur dioxide under mild conditions is reported. The sulfonylative couplings with the insertion of sulfur dioxide into C–H bonds are effective, and two classes of sulfonylative products are formed in moderate to good yields by the combination of radical chemistry and palladium-catalyzed C–H activation.