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Issue 90, 2017
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Exonuclease-assisted target recycling amplification for label-free chemiluminescence assay and molecular logic operations

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Abstract

A versatile exonuclease III (Exo III)-assisted target recycling amplification (Exo-TRA) strategy is demonstrated to achieve label-free and homogeneous chemiluminescence (CL) detection of target DNA. Inspired by this principle, a series of logic gates are constructed using DNA molecules as “inputs” to activate the Exo-TRA system.

Graphical abstract: Exonuclease-assisted target recycling amplification for label-free chemiluminescence assay and molecular logic operations

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Article information


Submitted
31 Aug 2017
Accepted
19 Oct 2017
First published
19 Oct 2017

Chem. Commun., 2017,53, 12201-12204
Article type
Communication

Exonuclease-assisted target recycling amplification for label-free chemiluminescence assay and molecular logic operations

Y. Yan, S. Yue, T. Zhao, B. Luo and S. Bi, Chem. Commun., 2017, 53, 12201
DOI: 10.1039/C7CC06835B

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