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Issue 77, 2017
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Highly selective tridentate fluorescent probes for visualizing intracellular Mg2+ dynamics without interference from Ca2+ fluctuation

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Abstract

We developed highly selective fluorescent Mg2+ probes based on a novel tridentate Mg2+-selective chelator. The superior selectivity for Mg2+ over Ca2+ enabled the detection of intracellular Mg2+ concentration changes without any response to Ca2+ influx. The new probes are potential keys to elucidating intracellular Mg2+ dynamics under conditions of extremely sharp Ca2+ fluctuation.

Graphical abstract: Highly selective tridentate fluorescent probes for visualizing intracellular Mg2+ dynamics without interference from Ca2+ fluctuation

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Article information


Submitted
06 Aug 2017
Accepted
30 Aug 2017
First published
30 Aug 2017

Chem. Commun., 2017,53, 10644-10647
Article type
Communication

Highly selective tridentate fluorescent probes for visualizing intracellular Mg2+ dynamics without interference from Ca2+ fluctuation

Y. Matsui, K. K. Sadhu, S. Mizukami and K. Kikuchi, Chem. Commun., 2017, 53, 10644
DOI: 10.1039/C7CC06141B

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