Issue 66, 2017
From the journal:

Chemical Communications

Dissecting the chloride–nitrate anion transport assay†

Yufeng Yang,ab   Xin Wu, ORCID logo c   Nathalie Busschaert, ORCID logo a   Hiroyuki Furuta ORCID logo b  and  Philip A. Gale ORCID logo *c  

* Corresponding authors

a Chemistry, University of Southampton, Southampton, UK

b Department of Chemistry and Biochemistry, Kyushu University, Fukuoka, Japan

c School of Chemistry, The University of Sydney, Australia
E-mail: philip.gale@sydney.edu.au

Abstract

A systematic study of chloride vs. nitrate selectivity across six anion transporters has revealed a good correlation between the selectivities of their anion binding and membrane transport properties. This work reveals the limitations of the chloride–nitrate exchange assay and shows how new approaches can be used to measure anion uniport.

Graphical abstract: Dissecting the chloride–nitrate anion transport assay

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Article information

DOI
https://doi.org/10.1039/C7CC04912A
Article type
Communication
Submitted
25 Jun 2017
Accepted
27 Jul 2017
First published
02 Aug 2017
This article is Open Access
Creative Commons BY license

Chem. Commun., 2017,53, 9230-9233

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Dissecting the chloride–nitrate anion transport assay

Y. Yang, X. Wu, N. Busschaert, H. Furuta and P. A. Gale, Chem. Commun., 2017, 53, 9230 DOI: 10.1039/C7CC04912A

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