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Issue 29, 2017
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A mitochondria-targeted fluorescent probe for imaging endogenous malondialdehyde in HeLa cells and onion tissues

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Abstract

The mitochondria-targeted turn-on fluorescent probe (Mito-FMP) based on a benzoxadiazole platform was developed for detection of malondialdehyde (MDA). Mito-FMP performed with large enhancement of the optical signal (774-fold) in response to MDA in an aqueous system and has the capability of monitoring endogenous MDA in HeLa cells and onion tissues.

Graphical abstract: A mitochondria-targeted fluorescent probe for imaging endogenous malondialdehyde in HeLa cells and onion tissues

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Supplementary files

Article information


Submitted
19 Jan 2017
Accepted
18 Mar 2017
First published
20 Mar 2017

Chem. Commun., 2017,53, 4080-4083
Article type
Communication

A mitochondria-targeted fluorescent probe for imaging endogenous malondialdehyde in HeLa cells and onion tissues

L. He, X. Yang, K. Xu and W. Lin, Chem. Commun., 2017, 53, 4080
DOI: 10.1039/C7CC00512A

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