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Issue 12, 2017
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A GSH-activatable ruthenium(ii)-azo photosensitizer for two-photon photodynamic therapy

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Abstract

A glutathione (GSH)-activatable ruthenium(II)-azo photosensitizer was prepared. The complex had low toxicity towards cells under dark conditions. It exhibited excellent phototoxicity under two-photon excitation (810 nm) and thus was developed as a two-photon photodynamic anticancer agent for cancer therapy.

Graphical abstract: A GSH-activatable ruthenium(ii)-azo photosensitizer for two-photon photodynamic therapy

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Supplementary files

Article information


Submitted
31 Dec 2016
Accepted
18 Jan 2017
First published
19 Jan 2017

Chem. Commun., 2017,53, 1977-1980
Article type
Communication

A GSH-activatable ruthenium(II)-azo photosensitizer for two-photon photodynamic therapy

L. Zeng, S. Kuang, G. Li, C. Jin, L. Ji and H. Chao, Chem. Commun., 2017, 53, 1977
DOI: 10.1039/C6CC10330H

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