Assembling gold nanoparticles into flower-like structures by complementary base pairing of DNA molecules with mediation by apoferritins

Abstract

Apoferritin caged gold nanoparticles (AuNPs) were assembled into flower-like structures by precise base pairing of the attached DNA molecules. The key step was to use the eight hydrophilic channels through the apoferritin to control the exact number and locations of the DNA molecules that grafted onto the caged AuNP.