Issue 4, 2017

Beyond chemotherapeutics: cisplatin as a temporary buckle to fabricate drug-loaded nanogels

Abstract

A cisplatin templated nanogel with targeting capability was synthesized, inspired by cisplatin as a chemotherapeutic drug. After crosslinking the natural polysaccharide hyaluronan, a ligand for CD44, cisplatin could be removed by simple dialysis in a salt solution while the withheld drug remains entrapped.

Graphical abstract: Beyond chemotherapeutics: cisplatin as a temporary buckle to fabricate drug-loaded nanogels

Supplementary files

Article information

Article type
Communication
Submitted
12 Oct 2016
Accepted
30 Nov 2016
First published
21 Dec 2016

Chem. Commun., 2017,53, 779-782

Beyond chemotherapeutics: cisplatin as a temporary buckle to fabricate drug-loaded nanogels

W. Zhang, Z. Zhang and C. Tung, Chem. Commun., 2017, 53, 779 DOI: 10.1039/C6CC08230K

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