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Issue 2, 2017
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Simultaneous detection of multiple targets involved in the PI3K/AKT pathway for investigating cellular migration and invasion with a multicolor fluorescent nanoprobe

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Abstract

We develop a multicolor fluorescent nanoprobe for assessing cellular migration and invasion by simultaneously imaging miRNA-221, PTEN mRNA and MMP-9 involved in the PI3K/AKT pathway which can regulate cellular mobility and invasiveness.

Graphical abstract: Simultaneous detection of multiple targets involved in the PI3K/AKT pathway for investigating cellular migration and invasion with a multicolor fluorescent nanoprobe

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Article information


Submitted
19 Sep 2016
Accepted
23 Nov 2016
First published
23 Nov 2016

Chem. Commun., 2017,53, 356-359
Article type
Communication

Simultaneous detection of multiple targets involved in the PI3K/AKT pathway for investigating cellular migration and invasion with a multicolor fluorescent nanoprobe

M. Luan, N. Li, W. Pan, L. Yang, Z. Yu and B. Tang, Chem. Commun., 2017, 53, 356
DOI: 10.1039/C6CC07605J

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