Issue 94, 2016

A fluorescent probe for the selective detection of creatinine in aqueous buffer applicable to human blood serum

Abstract

A naphthalimide-based fluorescence light-up probe, FCP–Pd, has been designed and synthesized for selective detection and quantitation of creatinine in PBS buffer of pH 7.2 at 37 °C with a ‘turn-on’ response over a variety of interfering metal ions and/or anions and several biologically significant species. This probe is highly effective in estimating creatinine in human blood serum, which confirms the reliability and accuracy of this new system to be applied in clinical and toxicological analysis.

Graphical abstract: A fluorescent probe for the selective detection of creatinine in aqueous buffer applicable to human blood serum

Supplementary files

Article information

Article type
Communication
Submitted
06 Sep 2016
Accepted
28 Oct 2016
First published
28 Oct 2016

Chem. Commun., 2016,52, 13706-13709

A fluorescent probe for the selective detection of creatinine in aqueous buffer applicable to human blood serum

S. Pal, S. Lohar, M. Mukherjee, P. Chattopadhyay and K. Dhara, Chem. Commun., 2016, 52, 13706 DOI: 10.1039/C6CC07291G

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