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Issue 80, 2016
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A fuel-limited isothermal DNA machine for the sensitive detection of cellular deoxyribonucleoside triphosphates

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Abstract

A fuel-limited isothermal DNA machine has been built for the sensitive fluorescence detection of cellular deoxyribonucleoside triphosphates (dNTPs) at the fmol level, which greatly reduces the required sample cell number. Upon the input of the limiting target dNTP, the machine runs automatically at 37 °C without the need for higher temperature.

Graphical abstract: A fuel-limited isothermal DNA machine for the sensitive detection of cellular deoxyribonucleoside triphosphates

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Article information


Submitted
21 Jul 2016
Accepted
05 Sep 2016
First published
07 Sep 2016

Chem. Commun., 2016,52, 11923-11926
Article type
Communication

A fuel-limited isothermal DNA machine for the sensitive detection of cellular deoxyribonucleoside triphosphates

J. Dong, T. Wu, Y. Xiao, L. Xu, S. Fang and M. Zhao, Chem. Commun., 2016, 52, 11923
DOI: 10.1039/C6CC05988K

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