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Issue 67, 2016
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Endocrine-specific NIR fluorophores for adrenal gland targeting

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Abstract

The adrenal glands (AGs) are relatively small yet require definitive identification during their resection, or more commonly their avoidance. To enable image-guided surgery involving the AGs, we have developed novel near-infrared (NIR) fluorophores that target the AGs after a single intravenous injection, which provided dual-NIR image-guided resection or avoidance of the AGs during both open and minimally-invasive surgery.

Graphical abstract: Endocrine-specific NIR fluorophores for adrenal gland targeting

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Supplementary files

Article information


Submitted
07 May 2016
Accepted
25 Jul 2016
First published
25 Jul 2016

Chem. Commun., 2016,52, 10305-10308
Article type
Communication

Endocrine-specific NIR fluorophores for adrenal gland targeting

Y. Ashitate, A. Levitz, M. H. Park, H. Hyun, V. Venugopal, G. Park, G. El Fakhri, M. Henary, S. Gioux, J. V. Frangioni and H. S. Choi, Chem. Commun., 2016, 52, 10305
DOI: 10.1039/C6CC03845J

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