Issue 49, 2016
From the journal:

Chemical Communications

Novel chiral Schiff base/Ti(iv) catalysts for the catalytic asymmetric epoxidation of N-alkenyl sulfonamides†

Nan Ji,a   Jiani Yuan,a   Miaoxi Liu,a   Ting Lana  and  Wei He*a  

* Corresponding authors

a Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 710032, P. R. China
E-mail: weihechem@fmmu.edu.cn

Abstract

A new method has been developed for the catalytic asymmetric epoxidation of N-alkenyl sulfonamides in the presence of a Schiff base derived from hydroquinine and Ti(Oi-Pr)4. This reaction proceeds under mild conditions, providing facile access to chiral epoxy sulfonamides in good yields (up to 95%) with excellent enantioselectivities (up to 97% ee).

Graphical abstract: Novel chiral Schiff base/Ti(iv) catalysts for the catalytic asymmetric epoxidation of N-alkenyl sulfonamides

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C6CC02852G
Article type
Communication
Submitted
06 Apr 2016
Accepted
16 May 2016
First published
19 May 2016

Chem. Commun., 2016,52, 7731-7734

Permissions

Request permissions

Novel chiral Schiff base/Ti(IV) catalysts for the catalytic asymmetric epoxidation of N-alkenyl sulfonamides

N. Ji, J. Yuan, M. Liu, T. Lan and W. He, Chem. Commun., 2016, 52, 7731 DOI: 10.1039/C6CC02852G

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements