Issue 50, 2016
From the journal:

Chemical Communications

Dynamic light scattering (DLS)-based immunoassay for ultra-sensitive detection of tumor marker protein†

Chao Li,‡a   Jiehua Ma,‡ab   Qiongxuan Fan,a   Yaqin Taoa  and  Genxi Li*ac  

* Corresponding authors

a State Key Laboratory of Pharmaceutical Biotechnology and Collaborative Innovation Center of Chemistry for Life Sciences, Department of Biochemistry, Nanjing University, Nanjing 210093, China
E-mail: Genxili@nju.edu.cn

b State Key Laboratory of Reproductive Medicine, Department of Reproductive Health, Nanjing Maternity and Child Health Care Hospital affiliated with Nanjing Medical University, Nanjing, Jiangsu, China

c Laboratory of Biosensing Technology, School of Life Sciences, Shanghai University, Shanghai 200444, China

Abstract

A novel dynamic light scattering (DLS)-based immunoassay that utilizes manganese dioxide nanosheet-modified gold nanoparticles (MnO2–GNPs) as an activatable nanoprobe has been developed to detect tumor markers down to femtomolar levels.

Graphical abstract: Dynamic light scattering (DLS)-based immunoassay for ultra-sensitive detection of tumor marker protein

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Article information

DOI
https://doi.org/10.1039/C6CC02633H
Article type
Communication
Submitted
29 Mar 2016
Accepted
23 May 2016
First published
24 May 2016

Chem. Commun., 2016,52, 7850-7853

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Dynamic light scattering (DLS)-based immunoassay for ultra-sensitive detection of tumor marker protein

C. Li, J. Ma, Q. Fan, Y. Tao and G. Li, Chem. Commun., 2016, 52, 7850 DOI: 10.1039/C6CC02633H

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