Jump to main content
Jump to site search

Issue 30, 2016
Previous Article Next Article

Unprecedented iron-catalyzed selective hydrogenation of activated amides to amines and alcohols

Author affiliations

Abstract

The first example of hydrogenation of amides homogeneously catalyzed by an earth-abundant metal complex is reported. The reaction is catalyzed by iron PNP pincer complexes. A wide range of secondary and tertiary N-substituted 2,2,2-trifluoroacetamides were hydrogenated to form amines and trifluoroethanol.

Graphical abstract: Unprecedented iron-catalyzed selective hydrogenation of activated amides to amines and alcohols

Back to tab navigation

Supplementary files

Publication details

The article was received on 18 Feb 2016, accepted on 10 Mar 2016 and first published on 10 Mar 2016


Article type: Communication
DOI: 10.1039/C6CC01505K
Chem. Commun., 2016,52, 5285-5288

  •   Request permissions

    Unprecedented iron-catalyzed selective hydrogenation of activated amides to amines and alcohols

    J. A. Garg, S. Chakraborty, Y. Ben-David and D. Milstein, Chem. Commun., 2016, 52, 5285
    DOI: 10.1039/C6CC01505K

Search articles by author

Spotlight

Advertisements