Jump to main content
Jump to site search

Issue 30, 2016
Previous Article Next Article

Unprecedented iron-catalyzed selective hydrogenation of activated amides to amines and alcohols

Author affiliations

Abstract

The first example of hydrogenation of amides homogeneously catalyzed by an earth-abundant metal complex is reported. The reaction is catalyzed by iron PNP pincer complexes. A wide range of secondary and tertiary N-substituted 2,2,2-trifluoroacetamides were hydrogenated to form amines and trifluoroethanol.

Graphical abstract: Unprecedented iron-catalyzed selective hydrogenation of activated amides to amines and alcohols

Back to tab navigation

Supplementary files

Article information


Submitted
18 Feb 2016
Accepted
10 Mar 2016
First published
10 Mar 2016

Chem. Commun., 2016,52, 5285-5288
Article type
Communication

Unprecedented iron-catalyzed selective hydrogenation of activated amides to amines and alcohols

J. A. Garg, S. Chakraborty, Y. Ben-David and D. Milstein, Chem. Commun., 2016, 52, 5285
DOI: 10.1039/C6CC01505K

Social activity

Search articles by author

Spotlight

Advertisements