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Issue 24, 2016
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Decorated self-assembling β3-tripeptide foldamers form cell adhesive scaffolds

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Abstract

A popular strategy to control cellular growth and differentiation is the employment of self-assembling peptides as biomaterials. In this study we decorated ultrashort helical N-acetylated β-tripeptides with cell adhesion signals IKVAV and RGD, which spontaneously self-assemble to give nanofibres with multiple signals, and form a bioscaffold that supports the growth of cells.

Graphical abstract: Decorated self-assembling β3-tripeptide foldamers form cell adhesive scaffolds

  • This article is part of the themed collection: Foldamers
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Supplementary files

Article information


Submitted
11 Jan 2016
Accepted
29 Feb 2016
First published
29 Feb 2016

Chem. Commun., 2016,52, 4549-4552
Article type
Communication

Decorated self-assembling β3-tripeptide foldamers form cell adhesive scaffolds

K. Luder, K. Kulkarni, H. W. Lee, R. E. Widdop, M. P. Del Borgo and M. Aguilar, Chem. Commun., 2016, 52, 4549
DOI: 10.1039/C6CC00247A

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