A membrane-anchored fluorescent probe for detecting K+ in the cell microenvironment

Mengyi Xiong; Huijie Zhu; Qiming Rong; Chan Yang; Liping Qiu; Xiao-Bing Zhang; Weihong Tan

doi:10.1039/C6CC00192K

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A membrane-anchored fluorescent probe for detecting K⁺ in the cell microenvironment†

Mengyi Xiong,^a Huijie Zhu,^a Qiming Rong,^a Chan Yang,^a Liping Qiu,^a Xiao-Bing Zhang*^a and Weihong Tan^a

Author affiliations

* Corresponding authors

^a Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Collaborative Innovation Center for Chemistry and Molecular Medicine, Hunan University, Changsha 410082, P. R. China
E-mail: xbzhang@hnu.edu.cn

Abstract

Cell-surface fluorescent probes are effective tools in cell biology and engineering. Here, we for the first time report a diacyllipid–aptamer conjugate-based fluorescent probe which could anchor on cell membrane for real-time tracking of potassium ions in the cell microenvironment.

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Article information

DOI: https://doi.org/10.1039/C6CC00192K
Article type: Communication
Submitted: 08 Jan 2016
Accepted: 01 Mar 2016
First published: 01 Mar 2016

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Chem. Commun., 2016,52, 4679-4682

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A membrane-anchored fluorescent probe for detecting K⁺ in the cell microenvironment

M. Xiong, H. Zhu, Q. Rong, C. Yang, L. Qiu, X. Zhang and W. Tan, Chem. Commun., 2016, 52, 4679 DOI: 10.1039/C6CC00192K

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Chemical Communications