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Issue 1, 2016
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A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines

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Abstract

Palladium catalysed three component cascade process, involving coupling of 2-iodobenzoates, -benzaldehydes, or acetophenones with substituted allenes and ammonium tartrate as an ammonium surrogate, provides a novel and facile route to substituted functionalised isoquinolinones and isoquinolines in good yields.

Graphical abstract: A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines

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Article information


Submitted
08 Sep 2015
Accepted
21 Oct 2015
First published
21 Oct 2015

Chem. Commun., 2016,52, 164-166
Article type
Communication
Author version available

A facile palladium catalysed 3-component cascade route to functionalised isoquinolinones and isoquinolines

R. Grigg, E. E. Elboray, S. Akkarasamiyo, N. Chuanopparat, H. A. Dondas, H. H. Abbas-Temirek, C. W. G. Fishwick, M. F. Aly, B. Kongkathip and N. Kongkathip, Chem. Commun., 2016, 52, 164
DOI: 10.1039/C5CC07526B

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