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Issue 2, 2016
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Enhancing the efficacy of cation-independent mannose 6-phosphate receptor inhibitors by intracellular delivery

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Abstract

Intracellular delivery of M6P/IGFII receptor inhibitors exhibits better efficacy than extracellular inhibitors to regulate TGFβ1 mediated upregulation of profibrotic marker, collagen I.

Graphical abstract: Enhancing the efficacy of cation-independent mannose 6-phosphate receptor inhibitors by intracellular delivery

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Publication details

The article was received on 14 Aug 2015, accepted on 19 Oct 2015 and first published on 19 Oct 2015


Article type: Communication
DOI: 10.1039/C5CC06826F
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Chem. Commun., 2016,52, 327-330

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    Enhancing the efficacy of cation-independent mannose 6-phosphate receptor inhibitors by intracellular delivery

    V. Agarwal, P. Toshniwal, N. E. Smith, N. M. Smith, B. Li, T. D. Clemons, L. T. Byrne, F. Kakulas, F. M. Wood, M. Fear, B. Corry and K. Swaminathan Iyer, Chem. Commun., 2016, 52, 327
    DOI: 10.1039/C5CC06826F

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