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Issue 100, 2015
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Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes

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Abstract

The amphiphilic polyene amphotericin B, a powerful treatment for systemic fungal infections, is shown to exhibit a critical aggregation concentration, and to form giant helically-twisted nanostructures via self-assembly in basic aqueous solution.

Graphical abstract: Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes

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Publication details

The article was received on 02 Oct 2015, accepted on 20 Oct 2015 and first published on 20 Oct 2015


Article type: Communication
DOI: 10.1039/C5CC08224B
Chem. Commun., 2015,51, 17680-17683
  • Open access: Creative Commons BY license
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    Self-assembly of the anti-fungal polyene amphotericin B into giant helically-twisted nanotapes

    I. W. Hamley, S. Kirkham, R. M. Kowalczyk, V. Castelletto, M. Reza and J. Ruokolainen, Chem. Commun., 2015, 51, 17680
    DOI: 10.1039/C5CC08224B

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