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Issue 98, 2015
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Self-sacrificial template-induced modulation of conjugated microporous polymer microcapsules and shape-dependent enhanced photothermal efficiency for ablation of cancer cells

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Abstract

The one-step synthesis of nanoscale conjugated microporous polymer (NCMP) capsules is presented by using PMAA microspheres as self-sacrificial templates. Precise control over the morphology, nanostructure and shell thickness makes the NCMPs have a tunable NIR absorption ability and a shape-dependent photothermal conversion efficiency. Upon exposure to 808 nm light, they rapidly generate heat (NCMP concentration: 100 μg mL−1) and cause thermal ablation of HeLa cells with less than 10% viability.

Graphical abstract: Self-sacrificial template-induced modulation of conjugated microporous polymer microcapsules and shape-dependent enhanced photothermal efficiency for ablation of cancer cells

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The article was received on 03 Jul 2015, accepted on 02 Oct 2015 and first published on 06 Oct 2015


Article type: Communication
DOI: 10.1039/C5CC05478H
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Chem. Commun., 2015,51, 17394-17397

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    Self-sacrificial template-induced modulation of conjugated microporous polymer microcapsules and shape-dependent enhanced photothermal efficiency for ablation of cancer cells

    J. Tan, J. Wan, J. Guo and C. Wang, Chem. Commun., 2015, 51, 17394
    DOI: 10.1039/C5CC05478H

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